Cellulite and localized fat, The skin | 2 October 2024

How to address cellulite? Discover the effective treatment for it

Cellulite, or orange-peel skin, is one of the most common aesthetic concerns, especially among women. Most people who suffer from it believe it has no remedy. However, fighting against and defeating cellulite is possible. In this article, we will explain what cellulite is, causes of its appearance, and how to prevent it. Additionally, we will explore one of the most innovative treatments to address it: the use of pbserum HA Medium recombinant enzymes. Thanks to its advanced formulation, which combines enzymes such as collagenase, lipase, and lyase, your skin will regain its firm, smooth, and healthy appearance. Moreover, this treatment is backed by solid scientific research demonstrating its efficacy and safety. After documenting more than 200 cases of patients treated with pbserum recombinant enzymes for managing skin laxity and fat accumulation, a high degree of patient satisfaction (over 85%) was reported, along with favorable aesthetic changes evaluated by the treating physicians.

What is cellulite?

Cellulite is an alteration of the subcutaneous cellular tissue caused by the accumulation of subcutaneous fat. Its appearance is more common among women due to differences in the distribution of fat, muscle, and connective tissue compared to men. It typically appears in areas where fat is more easily stored, such as the legs (mainly the thighs and buttocks), abdomen, and arms.

Classification

There are different types of cellulite classified based on their appearance and severity.

  • Soft cellulite: Often accompanied by skin laxity and is more visible when standing.
  • Hard cellulite: Found in areas where tissues are firmer.
  • Edematous cellulite: Associated with circulation and vascular conditions which traduce into fluid retention.

According to Doris Hexel severity scale (hexsel DM, et al. Int J Dermatol. 2000;39:539-4), we will find: *Grade I or mild. Hardly visible and almost without dimples. Its main characteristic is sagging skin, commonly appearing on the buttocks and legs. It usually affects sedentary individuals.

  • Grade II or moderate. Texture with evident dimples. Unlike Grade I, the skin has a firm appearance. It looks like orange-peel skin when pressed.
  • Grade III or severe. With deep dimples that make the skin surface bulge. It is common on the thighs, buttocks, and arms.
  • Grade IV or advanced cellulite. Also known as sclerotic cellulite, it presents large, deep, and very visible fat nodules. The classic “orange-peel” appearance is noticeable even at rest.

Regarding cellulite signs, the most common are:

  • Sagging and less firm skin in the affected areas.
  • Nodules and depressions that vary in size and distribution.
  • Irregular skin texture, with the appearance of characteristic dimples that give the “orange-peel skin” appearance.

Additionally, cellulite can cause increased sensitivity in the affected area. Some individuals may experience physical pain in these areas.

Common causes

Cellulite appears when connective tissue under the skin, is pushed by fat deposits. Factors contributing to its appearance can internal and external:

Internal factors that contribute to the development of cellulite

  • Genetic predisposition is the primary cause of appearance. Genetics affects on the skin elasticity, fat distribution and connective tissue structure.
  • Lifestyle is another major factor. An unbalanced diet and a sedentary lifestyle can worsen blood circulation and increase fluid retention and toxins within the
  • TraFeminine hormones, such as estrogens, may promote fat storage and affect collagen production and blood circulation.
  • Aging results in a loss of skin elasticity.

Influence of external factors

Among the most harmful external factors are:

  • Sedentary lifestyle: Lack of physical activity reduces blood and lymphatic blood circulation, promoting fat, toxins and fluid accumulation in the tissues.
  • Lack of hydration: Not drinking enoiugh water reduces skin firmness and elasticity. Moreover, it hinders toxin elimination through the lymphatic system.
  • Poor comsuption of fruits, vegetables and legumes and highly processed foods, fats and sugars, can lead to increased fat storage.
  • High stress levels, as well as chronic stress may affect the hormonal balance and increase fat accumulation.

Prevention tips

Changing to a healthier lifestyle, can help strenghten the skin and recover its elasticity. Try to:

  • Balance your diet by increasing the consumption of fresh fruits, vegetables and legumes.
  • Make sure to drink 2 liters of water a day to keep your skin hydrated and stimulate toxin elimination.
  • Exercise regularly, focusing on both cardio and strenght training to tone muscles and improve circulation. Start with brisk strolls of at least 30 minutes and gradually increase the duration.
  • Reduce the intake of alcochol, tobacco, soft drinks and over processed foods, to enhance your skin health.

Recombinant enzymes treatment option

pbserum recombinant enzymes are the result of years of biotechnological research, aimed at transformig with in the clinical practice the approach to treating different types of skin conditions and disorders. These enzymes act in a very specific and selective manner to , among other things:

  • Eliminate localized fat
  • Degrade old collagen fibers and stimulate new collagen formation
  • Improve microcirculation and lymphatic drainage

Recombinant enzymes provide visible and long- lasting results, as they act in the deeper layers of the skin. pbserum offers a wide range of products based on recombinant enzymes, each with different indications. Particularly, the HA Medium product is specifically designed to treat conditions related with fat accumulation. This include double chin, body fat and cellulite in various areas of the body. Its active ingredients include collgenase, lyase and lipase in higher concentrations.

Benefits and efficacy

Treatments with pbserum recombinant enzymes have become one of the most innovative for effectively treating cellulite in a more effective way. Among the benefits of using this method compared traditional ones are:

  • They are safer than the traditional tratments, as recombinant enzymes are biocompatible and substrate dependent, minimizing the risk of adverse effects. In the previously mentioned publication, none of the more than 200 patients treated, reported serious adverse effects or complications derived from pbserum´s recombinant enzymes.
  • They are minimally invasive treatments, requiring no prolonged recovery time and barely no side effects.
  • Optimal results are achieved after completing the protocol recommended by the medical specialist. The number of sessions ranges from 2 to 3.
  • Completely personalized treatments that adapt to each patient´s needs. Consulting a medical professional before starting the treatment, for is necessary, as it is important to assess the condition of the skin and affection type to advice a proper treatment.

In summary, cellulite is a visible skin condition, common among women and can beaddressest. A dietary change, engaging in physical activuty and proper hydration will help address it. Additionally-, treatments with recombinant enzymes improve the skin´s health and appearance.