Discover the power of recombinant enzymes

What are enzymes?

Enzymes are proteins that act as biological catalysts, speeding up essential chemical reactions without being consumed.

Recombinant enzymes are engineered using recombinant DNA technology, allowing for large-scale production with consistent quality.

pbserum's recombinant enzymes, developed through advanced biotechnological research in Albacete, Spain, utilize unique biotechnology to enhance regenerative treatments for various pathologies and skin disorders, revolutionizing global medicine and expanding therapeutic possibilities.

What are our enzymes?

Keratinase PB333

Keratinase PB333

It is a transepidermal dual delivery system that promotes cell renewal and increases permeability, while respecting the barrier effect of the skin, boosting the retention of active ingredients up to 9 times.

Hyaluronidase PB3000

Hyaluronidase PB3000

Catalyzes the breakdown of hyaluronic acid, reducing viscosity and improving the permeability of the extracellular matrix. As a result, it enhances microcirculation, promotes lymphatic drainage, and helps achieve a slimmer figure.

Collagenase PB220

Collagenase PB220

Breaks down aged collagen fibers and stimulates the production of new fibers by fibroblasts. This reduces the density of fibrotic tissue, improving flexibility and the overall structure of the treated area.

Lipase PB500

Lipase PB500

Activates lipid metabolism in the adipocyte, reducing localized fat without damaging the tissue. At the surface, it removes excess sebum, leaving the skin cleaner and improving its texture, while at the body level, it reduces volume and contours specific areas.

Lyase PB72K

Lyase PB72K

Degrades proteoglycans, increasing the fluidity and permeability of the extracellular matrix. This reduces fluid retention, decreases body volume, and enhances the appearance of the skin.

Our recombinant technology

pbserum has developed a unique two-generation technology using recombinant DNA to create bacterial-origin enzymes that mimic human enzymes.

Key highlights of pbserum enzymes include:

  • Efficacy and Safety: high substrate specificity and selectivity ensure effective treatment for a range of skin conditions, including wrinkles, scars, cellulite, and localized fat. Their role in tissue regeneration helps improve skin health and appearance.
  • Purity and Stability: achieved through a freeze-drying (lyophilization) process that dehydrates active ingredients by rapid freezing and sublimation under reduced pressure. This method maintains 100% enzyme activity and properties, ensuring product stability without the need for preservatives or additives.
  • Low Immunogenicity: recombinant technology ensures these enzymes have a low level of immunogenicity, making treatments safe and minimizing adverse immune responses.

These characteristics have enabled the development of safe and efficacious products for a range of treatments. By using pbserum's recombinant enzymes products, healthcare providers can offer advanced, safe, and effective treatments for various skin conditions, enhancing overall patient outcomes through innovative biotechnological solutions.

Who produces recombinant enzymes?

Proteos Biotech, founded in 2010, specializes in the research and production of recombinant enzymes for biomedicine and cosmetics. The company ensures high-quality standards through various certifications and supports the manufacture and supply of sterile pharmaceuticals, medical devices, and cosmeceuticals. Proteos Biotech is committed to innovation, evidenced by its participation in numerous R&D projects and its growing international recognition.

More info

Frequently
Asked
Questions

Lyophilization is a process of dehydration and freezing, thus obtaining a pure powder that keeps the enzymes inactive until reconstitution. This process does not induce degradation of the enzyme structure. Lyophilized enzymes can be stored at room temperature (ideally 25°C ± 5°C), without refrigeration. On the other hand, once reconstituted in saline solution, they should be applied immediately to ensure maximum effectiveness and to guarantee safety by avoiding contamination. As with all enzymes, there is an optimum temperature for their action which is in the range of 36 to 40°C.

  • Unique Recombinant Technology: Our enzymes are produced using a proprietary recombinant technology that ensures high purity, consistency, and efficacy.
  • Bacterial Origin: They are derived from bacterial sources, mimicking human enzymes for enhanced compatibility and effectiveness.
  • Strict Quality Standards: We operate under the most stringent health and manufacturing protocols, ensuring superior safety and reliability.
  • Global Validation: Our enzymes are recognized as a global standard, with extensive validation from thousands of patients and specialists across more than 50 countries. These factors combine to make pbserum’s enzymes a leading choice in the field.