The first treatment based on  Keratinase

What is Smarkter?

The first and only treatment with the power of Keratinase, and your best ally to enhance skin health and appearance.

smartker offers a Professional and Home skin-friendly treatment to adress most frequent concerns of patients, in all skin types all year round.

The versatility of this line allows it to be combined with any procedure in dermatology and aesthetic medicine, which facilitates its integration into daily clinical practice.

About our Keratinase PB333

It’s an enzyme obtained through recombinant technology, making it highly selective and acting on the specific substrate.

It acts as a transepidermal dual delivery system that promotes cell renewal and increases permeability, while respecting the barrier effect of the skin, boosting the retention of active ingredients up to 9 times.

Products

Professional Equilibrium & Daily Anti-Blemish

Chronoaging

Patients with early signs of aging, irregular texture and/or imperfections.

Active ingredients

Professional: Keratinase PB333, Vitamin A,C and E, and Hyaluronic Acid (HMW).

Daily: Keratinase PB333, Vitamin A,C and E, and Hyaluronic Acid (LMW).

Professional Multivit & Daily Oily Skin

Oily and/or acne-prone skin

Patients with acne-prone skin, active acne, altered sebum and enlarged pores.

Active ingredients

Professional: Keratinase PB333, Lipase PB500, Vitamin B complex (B1, B3, B5 and B6) and Hyaluronic Acid (HMW).

Daily: Keratinase PB333, Lipase PB500, Vitamin B3, B6 and Provitamin B5, Zinc Sulfate and Hyaluronic Acid (HMW).

Professional Radiant & Daily Radiant

Hyperpigmentation

Patients with visible hyperpigmentation, dull skin or uneven tone.

Active ingredients

Professional: Keratinase PB333, Vitamin C (20%) and Hyaluronic Acid (HMW).

Daily: Keratinase PB333, Vitamin C, Kojic Acid and Hyaluronic Acid (LMW).

Professional Hyaluronic & Daily Anti-Wrinkle

Loss of hydration

Patients with dry, dehydrated skin and visible expression lines.

Active ingredients

Professional: Keratinase PB333, Hyaluronic Acid (HMW and LMW).

Daily: Keratinase PB333, Alpinia Galanga Extract, Carnosine and Hyaluronic Acid (LMW).

Professional Firmness & Daily Firmness

Loss of firmness

Patients with signs of aging, facial flaccidity, loss of firmness and elasticity.

Active ingredients

Professional: Keratinase PB333, Collagenase PB220, Vitamin C, DMAE and Hyaluronic Acid (HMW).

Daily: Keratinase PB333, Collagenase PB220, Vitamin C, DMAE and Hyaluronic Acid (LMW).

Results

No skin alterations.(1)

According to the clinical examination performed by the dermatologist, none of the panelists showed any skin alteration 28 days after the continuous use of the product.

Up to a 30%(1)

improvement of the skin health.

Demonstrated efficacy and safety supported by 10 clinical studies, involving more than 200 patients, including sensitive skins.

> 85% (1) patients satisfied with the results after their smartker treatments.

8 out of 10 people would buy smartker products.

Before/After

Doctor's opinion

Discover more...

Frequently
Asked
Questions

The aim of the smartker line is to combine the Professional treatment (applied by the physician) with the Daily treatment (applied by the patient). The active ingredients of each formula complement each other to achieve an improvement of the problem to be treated. The benefits of Professional can be maintained with the Daily home treatment. The patient will be treated with smartker Professional once a week for 5 weeks, and will be combined with Smartker Daily daily by the patient for 30 days.

The recommended protocol consists of applying smartker professional once a week for 5 weeks, combined with smartker daily every day at night during the treatment period, with visible results from the first application. As in various aesthetic procedures, the protocols can be adapted according to the patient’s profile, the clinical need to be treated and the physician’s assessment.

SmartKer is an ideal treatment for all skin types, all year round. It has been evaluated by dermatologists in patients with sensitive skin, with no adverse events. All products have a low immunogenic potential and are gentle on the skin.

SmartKer contains keratinase, whose mechanism of action consists of increasing the permeability and, up to 9 times more, the retention of the active ingredients. It acts on the corneodesmosomes, which are reestablished in 6 to 8 hours, leaving the skin without side effects and can be used at any time of the year and on all phototypes, without leaving an aesthetic trace. On the other hand, a chemical peel is a controlled destruction of the skin layers through different acids. This brings with it side effects such as peeling, aesthetic trace, anti-inflammatory hyperpigmentation, burns… so it should not be used on all skin phototypes and is limited to certain times of the year due to the prohibition of sun exposure.

Do not apply in areas with skin infection, folliculitis or chronic acne in the area. The product is not injectable and is not recommended during pregnancy and lactation.

It is recommended to do the complete treatment: 5 weekly sessions of smartker professional combined with smartker Daily, for home use, for 1 month. It is also a versatile product that offers 3 options: Combination between products of the smartker line, with the help of other apparatology and after finishing other procedures.

(1) Data on file. Vv_et-sc20dxt2(d)-a_001_23_001 v1 equilibrium; vv_et-sc20dxt2(d)-a_001_22_002 v1 multivit; vv_et-1620dxt3(d)-a_001_23_001 v3 hyaluronic; vv_et-9+20dxt2(d)-a_001_23_001 v1 extreme firmness; vv_et-320dxt3(d)-a_001_23_001 v1 radiant. 2023.
*Study: Effectiveness and safety of pbserum Multivit Professional® Data on File 2024.