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Skin health, The skin | 4 December 2024

Improve your skin with Smartker, the first and only treatment with the power of Keratinase  

Discover the advanced treatments of pbserum Smartker, the only dual delivery system based on the power of Keratinase, the perfect ally to improve skin health and appearance.  

This range of products, highly effective, skin-friendly, easy to use, and compatible with any aesthetic procedure, has been formulated to address the most common patient skin concerns. 

Both the Professional line (Smartker Professional), used in the clinic, and the Homecare line (Smartker Daily), have been scientifically and dermatologically tested on all skin types, even the most sensitive ones.  

Learn how you can effectively and reliably improve issues such as oily and/or acne-prone skin, dryness, hyperpigmentation, and aging signs thanks to the power of Keratinase. 

Improve Your Skin: Advanced Solutions for Every Need

The skin is the largest organ of the human body and is exposed daily to factors that affect its appearance and health. As a result, various issues such as dry skin, hyperpigmentation, loss of firmness, or oily, acne-prone skin may arise.  

Fortunately, biotechnology has advanced significantly and offers solutions that were unthinkable a few years ago. In this article, we will explain the main patient needs and how the PB333 Keratinase enzyme from pbserum Smartker, present in their two treatment lines, can help you address them. 

pbserum Keratinase PB333: Cell Renewal and Skin Improvement

The Keratinase present in pbserum Smartker is especially effective in cell renewal and significantly improves skin texture and appearance.  

In the stratum corneum, the cells of this outermost layer of the epidermis are bound together by corneodesmosomes, creating a barrier that prevents the penetration of any external agents or substances.  

To overcome this obstacle, pbserum has formulated PB333 Keratinase.  

This recombinant enzyme, unique in the market and present in Smartker treatments, finds it´s substrate and targets keratin in the intermediate filaments of the corneodesmosomes, which bind the corneocytes together. Thanks to this mechanism, active ingredients penetrate the skin and reach the deeper layers of the epidermis, where they need to act. 

Most common skin concerns and how to treat them 

Oily skin and Acne 

Oily skin results from excessive sebum production, affecting people of all ages, and can lead to clogged pores and acne.  

  • How to treat it?: Keratinase allows the passage of active ingredients specifically thought to regulate sebum production, balance the skin, and improve its overall appearance. Smartker treatments help keep pores clean and reduce the buildup of dead cells, decreasing imperfections. pbserum offers two comprehensive solutions with an innovative and effective approach:
    • Professional treatment in clinics with Multivit Professional, its active ingredients are PB333 Keratinase, PB500 Lipase, Vitamins B1, B3, B5, and B6, and Hyaluronic Acid.
    • Homecare treatment with Daily Oily Skin, containing PB333 Keratinase, Vitamins B3, B5, and B6, Hyaluronic Acid, and Zinc Sulfate, which act as antimicrobial agents against acne-causing bacteria, have astringent properties, reduce pore size, control sebum production, and provide a tightening effect.

Being non-invasive treatments, there is a lower chance of causing irritation or side effects compared to other traditional methods. 

Hyperpigmentation 

Hyperpigmentation is characterized by the appearance of dark spots on the skin due to excessive melanin production often caused by sun exposure, genetic factors, hormonal changes, skin inflammation, or aging. 

  •  How to treat it?: Thanks to the mechanism of action of Keratinase, which allows the passage of active ingredients, it helps exfoliate the outermost layers and reduce melanin production in melanocytes, promoting a more even and luminous skin tone

pbserum offers two revolutionary lines whose clinical studies have demonstrated a depigmentation and tone unification of over 26%: 

  • Professional treatment in clinics with Radiant Professional, which include PB333 Keratinase, Vitamin C, and Hyaluronic Acid. 
  • Home treatment with Daily Radiant, whose formula includes PB333 Keratinase, Hyaluronic Acid, Vitamin C, and Kojic Acid. 

Firmness Loss 

Over time, the skin loses elasticity and firmness due to a decrease in collagen and elastin. Hormonal changes, sun exposure, or our lifestyle also play an important role in the process. Smartker treatments stimulate the production of these essential proteins, improving skin firmness and elasticity. 

  • How to treat it?: Keratinase facilitates the penetration of active ingredients, enhancing their rejuvenating effects.  
    • Smartker Firmness Professional and Daily are ideal for treating skin firmness and elasticity. Both formulations contain Keratinase PB333 which enhances the penetration of other active ingredients and promotes cell renewal; Collagenase G/H PB220, a recombinant enzyme that stimulates collagen production , improving skin firmness and elasticity;  Vitamin C, a potent antioxidant and essential ingredient for new collagen production and Hyaluronic Acid. 

Extreme Dryness

Extreme dryness is characterized by flaky, rough and sometimes itching skin.  Temperature changes, hygiene habits such as showering with very hot water or using strong soaps and detergents; aging, or possible medical conditions like psoriasis, hypothyroidism, or atopic dermatitis, can lead its  appearance. 

  • How to treat it?: Keratinase allows moisturizing actives to penetrate the skin , providing deep and long-lasting hydration. 
    • Smartker treatments restore the skin barrier and improve moisture retention, leaving a smooth and flexible skin: Smartker Hyaluronic products from the Professional and Daily Anti-Wrinkle lines are ideal for improving skin hydration. Both contain Keratinase and high and low molecular weight Hyaluronic Acid in their formula, which have a high capacity to attract and retain wáter, restoring hydration to the skin. 
    • Smartker Hyaluronic products from the Professional and Daily Anti-Wrinkle lines are ideal for improving skin hydration. Both contain Keratinase and high and low molecular weight Hyaluronic Acid in their formula, which have a high capacity to attract and retain wáter, restoring hydration to the skin. 
    • Smartker Daily Anti-Wrinkle also includes : Carnosine – a biomimetic peptide with anti-aging action that enhances collagen synthesis and protects the skin. Alpinia Galanga Extract, which stimulates the HAS-2 enzyme to improve skin hydration and reduce wrinkles.  

These ingredients, combined, provide deep hydration and improve the texture and appearance of the skin, making it look firmer and healthier. 

Chronoaging Signs 

Skin aging or chronoaging is a natural process that affects everyone.  

It manifests in the form of wrinkles, fine lines, skin spots, loss of firmness, and rougher skin texture.  

Factors such as environmental pollution, sun exposure, and lack of a proper skincare can accelerate the appearance of these signs in some people. 

  • How to treat it?: Keratinase promotes cell renewal and improves skin texture, visibly reducing aging signs. Smartker treatments, rich in recombinant enzymes, provide the necessary nutrients to achieve a younger and radiant skin.  
    • Smartker Equilibrium Professional and Smartker Daily Anti-Blemish, treat chronoaging. Both contain Keratinase, which facilitates the penetration of other active ingredients and promotes cell renewal.  Additionally, they are enriched with Vitamins A, C, and E, essential for enhancing the appearance, elasticity, and firmness of the skin. These vitamins play a crucial role in protecting against oxidative damage and stimulating collagen production. 

Regular use of these products helps address signs of chronoaging, resulting in a healthier and rejuvenated skin. 

Recombinant Enzymes benefits 

Recombinant enzymes used in smartker treatments are produced using advanced  recombinant biotechnology. These enzymes are purer, safer, and more effective compared to their natural counterparts.  Their benefits include: 

  • Specificity: They target the issue at hand without affecting the rest of the skin. Additionally, they allow a greater customization of dermatological treatments, as they can be designed and combined to address multiple skin concerns simultaneously. 
  • Good tolerance: Being biocompatible, there is less risk of adverse reactions or side effects compared to traditional chemical products. 
  • Non-invasive: Recombinant enzymes like keratinase, collagenase, and lipase are a safe option to address diverse skin concerns without the need for invasive procedures. This significantly reduces the risk of associated side effects. Moreover, as they are non-invasive, there is no recovery time required after use. 
  • Versalitily: They can be combined with other treatments or aesthetic procedures. 
  • Suitable for all skin types: even the most sensitive ones, and  can be ussed all year around. 

Why choose pbserum Smartker? 

pbserum Smartker is the first therapeutic system based on the recombinant enzyme Keratinase that has revolutionized the medical industry, significantly improving skin health and appearance.

The effectiveness of the line is supported by 10 clinical studies conducted on more than 200 patients using objective variables and without alterations to the skin.

These studies demonstrate an improvement of over 30% in skin health and appearance, with more than 85% of patients satisfied with the results after their Smartker treatment.

With pbserum Smartker, transform your skincare routine and enjoy a healthier, more radiant skin.

Furthermore, since recombinant enzymes are specific and non-invasive, the results are more effective with very few side effects.

If you want to discover the power of recombinant enzymes on your skin, now is the time to try Smartker, the personalized solution created for you by pbserum.